*Disseminated on Behalf of GT Biopharma, Inc. Please see disclosures below. |
| "GTBP" Working On Targeted Cancer Treatment |
| | | | | Folks, Most people have heard of immunotherapy by now — the idea that the body's own immune system can be trained to fight cancer instead of blasting patients with chemotherapy. It's been one of the biggest breakthroughs in medicine over the past decade.
The most famous version of this is called CAR-T therapy. Here's how it works: doctors take a patient's blood, extract their immune cells, genetically engineer them in a lab to recognize cancer, and then infuse them back into the patient.
It's been a game-changer for certain blood cancers!
But here's the problem — CAR-T is incredibly expensive (we're talking $400,000+ per treatment), takes weeks to manufacture for each individual patient, and comes with serious side effects. Some patients end up in the ICU from the treatment itself.
What if there was a simpler, cheaper, safer way to get the immune system to attack cancer?
That's exactly what GT Biopharma (NASDAQ: GTBP) is trying to do. | | | The Simple Version: What GT Biopharma Actually Does
The human body already has cells designed to kill cancer — they're called Natural Killer cells (NK cells).
The problem?
Cancer is sneaky. Tumors have developed ways to hide from these killer cells or shut them down. GT Biopharma has developed a drug that acts like a GPS guidance system for NK cells.
Think of it this way: imagine NK cells are heat-seeking missiles, but the cancer has turned off its heat signature. GT Biopharma's technology essentially paints a target on the cancer cells AND supercharges the missiles at the same time.
The company calls this their "TriKE" platform. Unlike CAR-T, this is an off-the-shelf drug — no genetic engineering required, no weeks of manufacturing for each patient. It's designed to work with the immune cells patients already have.
Why Big Pharma Is Paying Attention to This Space
GT Biopharma isn't operating in a vacuum. Major pharmaceutical companies have been pouring money into similar NK cell technologies:
✓ Sanofi paid $1 BILLION upfront to acquire Amunix and its immune cell technology ✓ Gilead paid $300 million upfront to license a single NK cell drug from Dragonfly Therapeutics ✓ Roche signed a deal worth up to $5 BILLION with Affimed for NK cell technology ✓ Sanofi expanded its partnership with Innate Pharma for up to €1.3 billion
The big players clearly see something here. The question is whether GT Biopharma can prove its technology works in humans.
What's In The Pipeline
GT Biopharma has multiple drugs in development, each designed to target different types of cancer: | | | Where They Are Today
The company's lead drug, GTB-3650, is currently in Phase 1 human trials for leukemia patients. The first patient was dosed on January 27, 2025, and as of October, the trial has advanced through four dose groups with six patients treated so far.
The early results?
No major safety issues have been reported, and blood tests show the drug is doing what it's supposed to do — activating and multiplying those cancer-killing NK cells. The company expects to share more detailed clinical data in early 2026.
Beyond Cancer: The Autoimmune Opportunity
Here's where it gets interesting...
The same technology that can target cancer cells might also work for autoimmune diseases like lupus. GT Biopharma's GTB-7550 is being developed to target the immune cells that go haywire in autoimmune conditions.
If this works, it could open up an entirely new market beyond oncology. | | | What GT Biopharma Has Going For It...
✓ Developing a potentially simpler, safer alternative to CAR-T cancer therapy ✓ Lead drug currently in human trials with early positive safety signals ✓ Big pharma has paid billions for similar technologies from competitors ✓ Second drug targeting solid tumors expected to enter trials in 2026 ✓ Potential expansion into autoimmune diseases like lupus ✓ Experienced management team with oncology drug development background
Anyways...
That's all for now!
Until Next Time, -ZT Team | P.S. Want our text alerts? Text "ZIPTRADER" to 1-(855)-228-1598 to sign up!
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*Disseminated on Behalf of GT Biopharma, Inc. Please see disclosures below. |
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