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Good day, 360! | Here are our top investing ideas today. And don't forget to join us in Market Masters - the hottest trading room around π₯. Be the best prepared trader on the Street! | | FOCUS LISTπ | NCNA - Up over 180% in pre after presenting encouraging Melanoma treatment data at ESMO Congress 2024 | ADAG- Up over 13% in pre after presenting positive results in Advanced/Metastatic Microsatellite-stable (MSS) Colorectal Cancer (CRC) treatment at ESMO Congress 2024 | ZNTL - Up over 36% in pre after announcing FDA has lifted partial clinical hold on Azenosertib Studies | | *sponsored by Stock Earnings | Gold's Booming, But These Gold Stocks are Doing Even Better | Physical gold protects your wealth, but miners are where the real action is. Here are 10 | gold stocks in particular to watch… | | Claim your free report now |
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| | HOTLISTπ₯ | NCNA - Up over 180% in pre after presenting encouraging Melanoma treatment data at ESMO Congress 2024 | NuCana plc (NCNA) is a clinical-stage biopharmaceutical company that engages in the development of medicines to treat patients with cancer. | Over the weekend, the company presented final data from the Phase 2 NuTide:701 study at the ESMO Congress on NUC-7738 in combination with pembrolizumab for patients with metastatic melanoma who were refractory to or had relapsed on prior PD-1 inhibitor therapy. | In this cohort of 12 patients, most of whom had received at least two prior lines of PD-1 inhibitor therapy, nine (75%) achieved disease control, including two patients who achieved Partial Responses. | One of these patients, who had received two prior lines of PD-1 inhibitor-based therapy and had progressed on their latest treatment of ipilimumab plus nivolumab within two months, achieved a 55% reduction in tumor volume. | Seven of the 12 patients had a progression free survival time of greater than five months, which is highly atypical in this patient population. In addition to achieving these encouraging efficacy signals, the combination of NUC-7738 and pembrolizumab had a favorable safety profile. | The stock traded up over 180% in the pre-market in reaction to the positive results. | | The first target for bulls is the prior resistance area at $7.96. Above that the pre-market high at $9.69 comes into play. Beyond that, targets to the upside are $10.79, $12 and $20. | Below $7.96, targets to the downside are $7, $6.58, $5, $4.30, $3.30 and then a gap fill at $2.54. | | ADAG- Up over 13% in pre after presenting positive results in Advanced/Metastatic Microsatellite-stable (MSS) Colorectal Cancer (CRC) treatment at ESMO Congress 2024 | Adagene Inc. (ADAG) is a clinical stage biotechnology company that engages in the research, development, and production of monoclonal antibody drugs for cancers. | Over the weekend, the company announced new ADG126 clinical data presented at the ESMO Congress, taking place in Barcelona, Spain, September 13-17. | Highlights include: | - Confirmed partial responses (PRs) doubled to four since ASCO GI in MSS CRC patients without liver and peritoneal metastases for overall response rate (ORR) of 24% (4/17) with ADG126 10 mg/kg every three weeks (Q3W) in combination with pembrolizumab - | - Median progression-free survival of 8.5 months observed in patients without liver and peritoneal metastases at the ADG126 10 mg/kg Q3W dose - | - At the 10 mg/kg dose level, 12-month overall survival (OS) rates were 74% for patients without liver metastases, and 82% for those without liver and peritoneal metastases - | - Safety profile maintained, with only 16% Grade 3 TRAEs in patients treated with ADG126 10 mg/kg Q3W in combination with pembrolizumab - | - Combination shows potential with standard of care to address broader patient populations, including MSS CRC patients with liver metastases - | The stock traded up over 13% in the pre-market in reaction to the positive news. | | The first target for bulls is the pre-market high at $4.01. | Beyond that, $4.30, $5, and $5.75 come into play. | Below $4.01, targets to the downside are $3.80, $3.60 and then a gap fill at $3.49 with $3 below that. | | Are you in Bullseye Trades yet? | If not… you missed DJT for the WIN! |  | *Trading is hard, results not guaranteed and should not be expected to be replicated typically. |
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| | | ZNTL - Up over 36% in pre after announcing FDA has lifted partial clinical hold on Azenosertib Studies | Zentalis Pharmaceuticals Inc. (ZNTL) is a clinical-stage biopharmaceutical company that focuses on discovering and developing small molecule therapeutics for the treatment of various cancers. | In the pre-market this morning, the company announced that the U.S. Food and Drug Administration (FDA) has lifted the partial clinical hold on studies of Azenosertib, the Company's novel, selective, and orally bioavailable inhibitor of WEE1. | The FDA has cleared the company to resume enrollment in all ongoing Azenosertib clinical studies with no changes in the clinical development plan. Zentalis will be working with clinical trial investigators to resume study activities across the Azenosertib development program as quickly as possible. | The Company remains on track to meet all previously disclosed data guidance for the remainder of 2024. | The stock traded up over 36% in the pre-market in reaction to the news. | | The first target for bulls is the pre-market high at $4.84. | Beyond that, $5.47, $5.70, $6.40 and $8.39 come into play. | Below $4.84, targets to the downside are $4.16, $4, $3.80, $3.60 and then a gap fill at $3.24. | | MARKET NEWS π° | | | P.S. Make sure you text "RAGE" to (888) 404-5747 to get all of our latest HOT STOCK ideas! | | Questions or concerns about our products? 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